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David A. Sinclair, Ph.D. is an entrepreneur, tenured professor at Harvard Medical School, and world leader in aging research. He has published over 160 scientific papers, is a co-inventor on over 50 patents, and has co-founded 12 biotechnology companies in the areas of aging, vaccines, diabetes, fertility, cancer, and biodefense. David is the author of the bestselling book Lifespan: Why We Age―and Why We Don’t Have To. He serves as co-chief editor of the scientific journal Aging, works with national defense agencies, and works with NASA. He has received 35 honors including being one of Australia’s leading scientists under 45, TIME magazine’s list of the “100 most influential people in the world” and many more.
For the full episode transcript, all the show notes, research, links and much more – visit the episode page here: https://www.successpodcast.com/show-notes/2020/7/30/how-to-stop-amp-reverse-aging-with-dr-david-sinclair?rq=David%20Sinclair
SHOW NOTES & TIMESTAMPS
01:44 Introduction and David Sinclair Bio
02:29 Interview Begins
03:00 Is Aging Natural?
04:01 Resetting the Biological Clock
06:39 Aging at the Cellular Level
10:58 What is the difference between the genome of the epigenome and how do they interact in the body?
14:29 Lifespan controlled by Genetics (20%) and Epigenetics (80%)
15:18 How does Epigenetic Reprogramming take place?
18:54 How much variance can there be between your biological age and your chronological age?
19:57 Activities that reduce caused mortality
21:19 How Epigenetic Reprogramming Occurs and Ways to Support It
24:02 What are some of the strategies for making your sirtuins more effective?
27:19 Why fasting is so effective
30:09 How does cold exposure work to reverse or slow the aging process?
33:46 Importance of external stressors to keep your sirtuins proactive
35:29 Modern comforts making us more prone to aging
36:49 The process of aging reversal
40:27 Future of Age Reversing Science
42:40 The What and Why of the Supplements David takes to Mitigate Aging Effects
48:58 What can you start doing now?
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